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FAUCHIER LAURENT


Cardiologue
. Membre permanent d’EES

A/ Présentation des thèmes de recherche

Les travaux effectués ces dernières années témoignent de la pertinence des questions de l’équipe pour le domaine de la cardiologie. On y retrouve des recoupements pour les questions de stratification du risque (avec élaboration d’outils spécifiques, par exemple sous forme de score de risque, ainsi que leur évaluation ou leur validation), du vieillissement des populations avec des pathologies cardiaques posant des questions sur les fins de vie et les modes de décès, d’évaluation des coûts de santé à l’échelle de la population et des rapports bénéfice/risque des thérapeutiques en cardiologie, et de l’optimisation des décisions pour les prise en charge en cardiologie (comprenant d’une part la participation à l’élaboration de documents de synthèse et de recommandations, et d’autre part des études sur l’impact et l’applicabilité des recommandations). 

B/ Publications
. Marijon E, Fauchier L, Le Heuzey J-Y. New antithrombotic drugs and European approval processes. Lancet 2011;378:662–663.
. Marijon E, Le Heuzey J-Y, Fauchier L. Review of novel therapeutics by three regulatory agencies. N Engl J Med 2012;367:1166; author reply 1166-1167.
. Lip GYH, Banerjee A, Lagrenade I, Lane DA, Taillandier S, Fauchier L. Assessing the risk of bleeding in patients with atrial fibrillation: the Loire Valley Atrial Fibrillation project. Circ Arrhythm Electrophysiol 2012;5:941–948.
. Olesen JB, Fauchier L, Lane DA, Taillandier S, Lip GYH. Risk factors for stroke and thromboembolism in relation to age among patients with atrial fibrillation: the Loire Valley Atrial Fibrillation Project. Chest 2012;141:147–153.
. Banerjee A, Fauchier L, Vourc’h P, Andres CR, Taillandier S, Halimi JM, Lip GYH. Renal impairment and ischemic stroke risk assessment in patients with atrial fibrillation: the Loire Valley Atrial Fibrillation Project. J Am Coll Cardiol 2013;61:2079–2087.
. Hanon O, Assayag P, Belmin J, Collet JP, Emeriau JP, Fauchier L, Forette F, Friocourt P, Gentric A, Leclercq C, Komajda M, Le Heuzey JY, French Society of Geriatrics and Gerantology, French Society of Cardiology. Expert consensus of the French Society of Geriatrics and Gerontology and the French Society of Cardiology on the management of atrial fibrillation in elderly people. Arch Cardiovasc Dis 2013;106:303–323.
. Hanon O, Assayag P, Belmin J, Collet JP, Emeriau JP, Fauchier L, Forette F, Friocourt P, Gentric A, Leclercq C, Komajda M, Le Heuzey JY, French society of geriatrics and gerontology and the French society of cardiology. [Expert consensus of the French society of geriatrics and gerontology and the French society of cardiology on the management of atrial fibrillation in elderly people]. Gériatrie Psychol Neuropsychiatr Vieil 2013;11:117–143.
. Brunet-Bernard A, Maréchaux S, Fauchier L, Guiot A, Fournet M, Reynaud A, Schnell F, Leclercq C, Mabo P, Donal E. Combined score using clinical, electrocardiographic, and echocardiographic parameters to predict left ventricular remodeling in patients having had cardiac resynchronization therapy six months earlier. Am J Cardiol 2014;113:2045–2051.
. Lip GYH, Haguenoer K, Saint-Etienne C, Fauchier L. Relationship of the SAMe-TT₂R₂ score to poor-quality anticoagulation, stroke, clinically relevant bleeding, and mortality in patients with atrial fibrillation. Chest 2014;146:719–726.
. Banerjee A, Fauchier L, Bernard-Brunet A, Clementy N, Lip GYH. Composite risk scores and composite endpoints in the risk prediction of outcomes in anticoagulated patients with atrial fibrillation. The Loire Valley Atrial Fibrillation Project. Thromb Haemost 2014;111:549–556.
. Fauchier L, Angoulvant D, Lip GYH. The SAMe-TT2R2 score and quality of anticoagulation in atrial fibrillation: a simple aid to decision-making on who is suitable (or not) for vitamin K antagonists. Eur Eur Pacing Arrhythm Card Electrophysiol J Work Groups Card Pacing Arrhythm Card Cell Electrophysiol Eur Soc Cardiol 2015;17:671–673.
. Fauchier L, Marijon E, Defaye P, Piot O, Sadoul N, Perier M-C, Gras D, Klug D, Algalarrondo V, Bordachar P, Deharo J-C, Leclercq C, Babuty D, Boveda S, DAI-PP Investigators. Effect of age on survival and causes of death after primary prevention implantable cardioverter-defibrillator implantation. Am J Cardiol 2015;115:1415–1422.
. Philippart  R, Brunet-Bernard A, Clementy N, Bourguignon T, Mirza A, Babuty D, Angoulvant D, Lip GY, Fauchier L.  Prognostic value of CHA2DS2-VASc score in patients with 'non-valvular atrial fibrillation' and valvular heart disease: the Loire Valley Atrial Fibrillation Project. Eur Heart J. 2015 Jul 21;36(28):1822-30. doi: 10.1093/eurheartj/ehv163.
. Fauchier  L, Clementy N, Pelade C, Collignon C, Nicolle E, Lip GY. Patients With Ischemic Stroke and Incident Atrial Fibrillation: A Nationwide Cohort Study. Stroke. 2015 Sep;46(9):2432-7. doi: 10.1161/STROKEAHA.115.010270. Epub 2015 Aug 6.
. Fauchier L, Poli D, Olshansky B.The SAMe-TT2R2 score and quality of anticoagulation in AF: Can we predict which patient benefits from anticoagulation? Thromb Haemost. 2015 Oct;114(4):657-9. doi: 10.1160/TH15-06-0518.
. Cotté FE, Chaize G, Gaudin AF, Samson A, Vainchtock A, Fauchier L. Burden of stroke and other cardiovascular complications in patients with atrial fibrillation hospitalized in France. Europace. 2016 Apr;18(4):501-7. doi: 10.1093/europace/euv248.
. Wilkoff BL, Fauchier L, Stiles MK, Morillo CA, Al-Khatib SM, Almendral J, Aguinaga L, Berger RD, Cuesta A, Daubert JP, Dubner S, Ellenbogen KA, Mark Estes NA 3rd, Fenelon G, Garcia FC, Gasparini M, Haines DE, Healey JS, Hurtwitz JL, Keegan R, Kolb C, Kuck KH, Marinskis G, Martinelli M, McGuire M, Molina LG, Okumura K, Proclemer A, Russo AM, Singh JP, Swerdlow CD, Teo WS, Uribe W, Viskin S, Wang CC, Zhang S. 2015 HRS/EHRA/APHRS/SOLAECE expert consensus statement on optimal implantable cardioverter-defibrillator programming and testing. Heart Rhythm. 2016 Feb;13(2):e50-86. doi: 10.1016/j.hrthm.2015.11.018
. Ancedy Y, Lecoq C, Saint Etienne C, Ivanes F, Angoulvant D, Babuty D, Lip GY, Fauchier L. Antithrombotic management in patients with atrial fibrillation undergoing coronary stent implantation: What is the impact of guideline adherence? Int J Cardiol. 2016 Jan 15;203:987-94. doi: 10.1016/j.ijcard.2015.11.090.
. Diamantopoulos A, Sawyer LM, Lip GY, Witte KK, Reynolds MR, Fauchier L, Thijs V, Brown B, Quiroz Angulo ME, Diener HC. Cost-effectiveness of an insertable cardiac monitor to detect atrial fibrillation in patients with cryptogenic stroke. Int J Stroke. 2016 Apr;11(3):302-12. doi: 10.1177/1747493015620803.
. Fauchier L, Chaize G, Gaudin AF, Vainchtock A, Rushton-Smith SK, Cotté FE. Predictive ability of HAS-BLED, HEMORR2HAGES, and ATRIA bleeding risk scores in patients with atrial fibrillation. A French nationwide cross-sectional study. Int J Cardiol. 2016 Aug 15;217:85-91. doi: 10.1016/j.ijcard.2016.04.173.
. Fauchier L, Clementy N, Bisson A, Ivanes F, Angoulvant D, Babuty D, Lip GY. Should Atrial Fibrillation Patients With Only 1 Nongender-Related CHA2DS2-VASc Risk Factor Be Anticoagulated? Stroke. 2016 Jul;47(7):1831-6. doi: 10.1161/STROKEAHA.116.013253.
. Fauchier L, Villejoubert O, Clementy N, Bernard A, Pierre B, Angoulvant D, Ivanes F, Babuty D, Lip GY. Causes of Death and Influencing Factors in Patients with Atrial Fibrillation. Am J Med. 2016 Jul 28. pii: S0002-9343(16)30732-X. doi: 10.1016/j.amjmed.2016.06.045.
. Fauchier L, Lecoq C, Ancedy Y, Stamboul K, Saint Etienne C, Ivanes F, Angoulvant D, Babuty D, Cottin Y, Lip GY. Evaluation of 5 Prognostic Scores for Prediction of Stroke, Thromboembolic and Coronary Events, All-Cause Mortality, and Major Adverse Cardiac Events in Patients With Atrial Fibrillation and Coronary Stenting. Am J Cardiol. 2016 Sep 1;118(5):700-7. doi: 10.1016/j.amjcard.2016.06.018.
. Lip GY, Fauchier L, Freedman SB, Van Gelder I, Natale A, Gianni C, Nattel S, Potpara T, Rienstra M, Tse HF, Lane DA. Atrial fibrillation. Nat Rev Dis Primers. 2016 Mar 31;2:16016. doi: 10.1038/nrdp.2016.16.
. Piccini JP, Fauchier L. Rhythm control in atrial fibrillation. Lancet. 2016 Aug 20;388(10046):829-40.
. Darwiche W, Bejan-Angoulvant T, Angoulvant D, Babuty D, Fauchier L. Risk of myocardial infarction and death in patients with atrial fibrillation treated with dabigatran or vitamin K antagonists. Meta-analysis of observational analyses. Thromb Haemost. 2016 Sep 1;116(5). 

C/ Recherches et interventions

. Expert pour Archives des Maladies du Coeur et des Vaisseaux, Annales de Cardiologie et d’Angéiologie, The American Journal of Cardiology, American Journal of Hypertension, American Journal of Physiology - Heart and Circulatory Physiology, Circulation, Coronary Artery Disease, Critical Care Medicine, Europace, Journal of the American College of Cardiology, Journal of Applied Physiology, European Heart Journal, Heart, Obesity Research, The Lancet, Thrombosis Haemostasis.
 


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